Martine Largeron (Dr)
Dr Martine Largeron
University of Paris Descartes Phone: (+33)15373 9646
UMR CNRS 8638 Email: martine.largeron@parisdescartes.fr
Faculty of Pharmacy of Paris
4 avenue de l’Observatoire
75270 Paris cedex 06, France
Current research interests
Homogeneous catalysis: the emphasis is placed on bioinspired oxidative processes;
Biomimetic electrosynthesis: especially to mimic the biosynthesis of natural products.
Academic appointment
2004-present :Director of Research at the CNRS (Senior Scientist)
UMR 8638 CNRS-University Paris Descartes
2016
Catalytic oxidative coupling of primary amines under air: A flexible route to benzimidazole derivatives.
Khac Minh Huy Nguyen, Martine Largeron
European Journal of Organic Chemistry, 2016, 1025-1032.
2015
A Bioinspired catalytic aerobic oxidative C-H functionalization of primary aliphatic amines: synthesis of 1,2-disubstituted benzimidazoles.
Khac Minh Huy Nguyen, Martine Largeron
Chemistry - A European Journal, 2015, 21, 12606-12610 (Hot Paper).
http://www.cnrs.fr/inc/communication/direct_labos/largeron.htm
Polycyclic Polyprenylated Xanthones from Symphonia globulifera: Isolation and Biomimetic Electrosynthesis.
Kévin Cottet, Anne Neudörffer, Marina Kritsanida, Sylvie Michel, Marie-Christine Lallemand, Martine Largeron
Journal of Natural Products, 2015, 78, 2136-2140.
Regiospecific synthesis of neuroprotective 1,4-benzoxazine derivatives through a tandem oxidation-Diels-Alder reaction.
Khac Minh Huy Nguyen, Leslie Schwendimann, Pierre Gressens, Martine Largeron.
Organic and Biomolecular Chemistry, 2015, 13, 3749-3756.
A metalloenzyme-like catalytic system for the chemoselective oxidative cross-coupling of primary amines to imines under ambient conditions.
Martine Largeron, Maurice-Bernard Fleury
Chemistry- A European Journal, 2015, 21, 3815-3820.
2013
Protocols for the catalytic oxidation of primary amines to imines.
Martine Largeron
European Journal of Organic Chemistry, 2013, 5225-5235 (Microreview).
Bioinspired Oxidation Catalysts.
Martine Largeron, Maurice-Bernard Fleury
Science, 2013, 339, 43-44 (Perspective).
2012
A Biologically inspired Cu(I)/topaquinone-like co-catalytic system for the highly atom economical aerobic oxidation of primary amines to imines.
Martine Largeron, Maurice-Bernard Fleury
Angewandte Chemie International Edition, 2012, 51, 5409-5412.
A convenient biomimetic synthesis of optically active putative neurotoxic metabolites of MDMA “ecstasy” from R-(-)- and S-(+)-N-methyl-a-methyldopamine precursors.
Claire-Marie Martinez, Anne Neudörffer, Martine Largeron
Organic and Biomolecular Chemistry, 2012, 10, 3739-3748.